Search results for "Dead Volume"
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Impulse response tests in completely mixed tanks and reactors. Key assumptions and steps in mathematical developments.
2010
Stimulus-response technique is a method to obtain the Residence Time Distribution (RTD) for the elements of a fluid passing through a vessel. Generally speaking, in reactor science unsteady-state tests may often appear preferable to steady-state since they are made up of a chain of intermediate ones; but without any theoretical necessity holding. In RTD studies, however, non-steady state tests are the only conceivable ones if conservative tracers are employed, because once a transition is over there is no way to reconstruct it and assess the hydraulic behaviour of the tank. Only a series of tests with non-conservative tracers of known disappearance rate would achieve the task, but at the pr…
Stationary phase modulation in liquid chromatography through the serial coupling of columns: A review
2016
Liquid chromatography with single columns often does not succeed in the analysis of complex samples, in terms of resolution and analysis time. A relatively simple solution to enhance chromatographic resolution is the modulation of the stationary phase through the serial coupling of columns. This can be implemented with any type of column using compatible elution conditions and conventional instruments. This review describes the key features of column coupling and published procedures, where two or more columns were coupled in series to solve separation problems. In all reports, the authors could not resolve their samples with single columns, whereas significant enhancement in chromatographi…